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Parkinson’s and Male Sexual Health

How does PD play a part in Erectile Dysfunction in men?

  • Male impotence, otherwise known as erectile dysfunction (ED), refers to difficulty with achieving and maintaining an adequate erection.
  • The release and widespread use of treatments for ED has proved helpful in many cases.
  • While these medications are contraindicated in certain heart conditions, they are generally safe to use in combination with antiparkinson’s medications and more effective in younger age groups.
  • As with other non-motor symptoms, the doctor or other health care provider should consider other causes of impotence and decreased libido, including poor circulation to the genitals that commonly occurs in diabetes and peripheral vascular disease, enlarged prostate, depression and other medical conditions.
  • Erectile dysfunction warrants a thorough evaluation so the physician or other health care provider can look for all possible causes, especially diabetes (which can cause autonomic neuropathy) and other disorders listed above.
  • The general physician and urologist should conduct a complete physical examination.
  • The list of drugs available to treat ED has been upgraded in the last decade from those that must be injected into the penis to oral preparations.

Medications to Treat Erectile Dysfunction in Men with PD

 Erectile Dysfunction Injectibles:

  • Papaverine HCI (Papaverine® vials for injection)
  • Phentolamine (Regitine® vials for injection)
  • Alprostadil (Caverject®)

Oral preparations:

  • Sildenafil (Viagra®)
  • Vardenafil (Levitra®)
  • Tadalafil (Cialis®)
  • Yohimbine (Yocon®)

Page reviewed by Dr. Joash Lazarus, NPF Movement Disorders Fellow, Department of Neurology at Emory University School of Medicine.