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Podcast Series

Substantial Matters: Life and Science of Parkinson’s

Every other week, we bring you a new episode of Substantial Matters: Life and Science of Parkinson’s. Host Dan Keller, PhD, interviews Parkinson’s experts to highlight the treatments and techniques that can help you live a better life now, as well as the research that can bring a better tomorrow. Episodes focus on a range of topics relevant to your daily life, including new levodopa delivery methods, exercise, clinical trials, nutrition and more!

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To get started, listen to the episodes in the following playlist, or learn more about each episode below.

If you would like to suggest a topic for the podcast, or if you have questions or feedback after listening, let us know at www.parkinson.org/feedback.

Episode 7: Genetics as a Guide to Neuroprotection in Parkinson’s Disease

David K. Simon, MD, PhD, explains how modern genetics can be a guide to developing new drugs for Parkinson's.  More Info

Episode 6: New Levodopa Delivery Methods for Parkinson’s

More than 50 years after its discovery, levodopa is still the most effective treatment for Parkinson’s, but some people experience “off” periods or dyskinesias with oral medications. Dr. Mark Guttman describes new delivery methods that promise to help with some of these problems, especially for people who have had Parkinson’s for many years. More Info

Episode 5: How to Manage Parkinson’s “Off” Time

Parkinson’s can be unpredictable – symptoms can come and go or get better and worse throughout the day. These so-called “on-off” fluctuations (also called motor fluctuations) and dyskinesias can be troubling, but movement disorder specialists can help with the choice of medication, dosages, and timing. Dr. Irene Malaty explains more about what causes these changes and how you can work with your doctor to manage them. More Info

Episode 4: The Importance of Good Nutrition for People with Parkinson’s

Nutrition is increasingly part of the conversation when it comes to good Parkinson's care. Dr. Bas Bloem describes how diet can help improve some of the symptoms of Parkinson's and optimize the effects of medication, and he offers tips on getting adequate nutrition. More Info

Episode 3: The Benefits of Exercise for People with Parkinson's

Regular exercise is essential for people with Parkinson's. Dr. Bas Bloem describes what is known about exercise and PD and what is still in the research stages, and he offers some tips on overcoming barriers to getting enough exercise. More Info

Episode 2: The Parkinson's Foundation’s Role in Improving Standards of Care

Dr. Peter Schmidt of the Parkinson’s Foundation explains where people with Parkinson’s can go to receive the best interdisciplinary care and how the Foundation is improving standards of Parkinson’s care around the world. The Foundation's Centers of Excellence network and the Parkinson's Outcomes Project are key aspects of the discussion. More Info

Episode 1: Early Warning Signs of Parkinson's

In this debut episode of Substantial Matters: Life and Science of Parkinson's, Dr. Michael Okun talks about early warning signs of Parkinson's and offers practical advice on how to proceed after a diagnosis. More Info