TOPAZ Trial

A COVID-19 update for the TOPAZ study: We are continuing to recruit for the study. Interested people can go through the online consent process, and, if necessary to confirm your PD diagnosis, can complete the telemedicine exam. If you are eligible to receive the study drug/infusion, your case will be put “on hold” until things change with COVID-19, and research study visits become plausible again.  

Join a Parkinson’s Study Without Ever Leaving Your Home

Did you know that people with Parkinson's disease (PD) have a higher risk of fractures?

Help us find a solution.
The TOPAZ study will test if a medicine called zoledronic acid can prevent fractures in people with PD. A team of doctors who are experts in bone health and PD are leading the study. The use of zoledronic acid in this study is investigational.

You can join if:

  • You have Parkinson's disease
  • Are 65 year old or older

The study is done from your home!

  • If you are eligible for the study, a nurse will come to your home to give you a short exam.
  • You'll receive a one-time dose of the study treatment (either zoledronic acid or a placebo)
  • During the study, we will contact you every four months to check if you have had any new fractures

Earn $100 upon enrollment and $50 per year during the study.

Want to learn more about joining TOPAZ? Visit https://topaz.eurekaplatform.org or call the Parkinson's Foundation Helpline at 1-800-4PD-INFO (473-4636).

This study is endorsed by the Parkinson's Foundation and the Parkinson's Study Group.

PF          PSG

Learn more about PD and bone health.

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