Podcast: Substantial Matters

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Every other Tuesday, we bring you a new episode of Substantial Matters: Life and Science of Parkinson’s. Host Dan Keller, PhD, interviews Parkinson’s experts to highlight the treatments and techniques that can help you live a better life now, as well as the research that can bring a better tomorrow. Episodes focus on a range of topics relevant to your daily life, including new levodopa delivery methods, exercise, clinical trials, nutrition and more!

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To get started, listen to the episodes in the following playlist, or learn more about each episode below.

Tell us what you think about the podcast here!

Click here to listen to our Spanish episodes

Podcast Episode 115: Repurposing Medications to Slow Progression of PD

In this podcast episode, Dr. Patrik Brundin, Director of the Parkinson’s Disease Center at Van Andel Institute in Grand Rapids, Michigan, explains the approach of drug repurposing to treat Parkinson’s disease. This approach relies on knowing the mechanisms of the disease and searching through the vast array of current drugs to treat all sorts of conditions and rationally choosing ones that may work to slow progression of PD.

Podcast Episode 114: Gene-Based Therapies for Parkinson’s Disease

In this second part of our series on Parkinson’s disease therapies, Dr. Roger Barker, Professor of Clinical Neuroscience at the University of Cambridge in the United Kingdom, explains gene-based therapy. Dr. Barker discusses plans for the execution of the treatments, what symptoms they are aimed at, where the field currently stands, and how it compares to developments in cell-based therapies.

Podcast Episode 113: Cell-Based Therapies for Parkinson’s Disease

In this podcast episode, Dr. Roger Barker, Professor of Clinical Neuroscience at the University of Cambridge in the United Kingdom, summarizes what has been learned so far about cell-based therapies for treating Parkinson’s disease.

Podcast Episode 112: Non-pharmaceutical Treatments for PD: DBS and Focused Ultrasound

In this podcast episode, Kyle Mitchell, MD of Duke University in North Carolina discusses two non-pharmaceutical treatments for Parkinson's disease: deep brain stimulation (DBS) and focused ultrasound (FUS). Dr. Mitchell discusses how each treatment works, which patients may do best with either of them, and what is in development.

Podcast Episode 111: Alone in a Crowd: Overcoming Isolation

In this podcast episode, Aaron Daley, Coordinator for the Parkinson’s Disease Clinic and Research Center at the University of California, San Francisco, discusses social isolation and ways to overcome it, whether you live in an urban or rural area. He recommends seeking out support, exercising regularly, or establishing a routine of activity with a companion.

Podcast Episode 110: Social Isolation and Loneliness

In this podcast episode, Dr. Indu Subramanian, Director of the Parkinson’s Disease Research, Education and Clinical Center at the West Los Angeles Veterans Affairs Medical Center, discusses loneliness and social isolation and offers suggestions for keeping them at bay.

Podcast Episode 109: Medication Timing

In this podcast episode, Dr. Indu Subramanian, Director of the Parkinson’s Disease Research, Education and Clinical Center at the West Los Angeles Veterans Affairs Medical Center, discusses what has been learned about the timing of the initiation of therapy. She also provides strategies for getting the most benefit from medications.

Bonus Episode en Español: Deshaciendo la barrera del idioma con una clínica hispana

In our ongoing efforts to reach all communities whose members may be affected by Parkinson's disease, this week's episode will be in Spanish. We will return with more English language podcasts in two weeks. In this episode, we speak with neurologist María Luisa Moro about her work in developing Connecticut’s first Parkinson’s clinic dedicated to serving the Spanish-speaking community.

Podcast Episode 108: The Golden Year for Testing Disease Modifying Drugs

In this podcast episode, Dr. Robert Hauser, Director of the Parkinson’s Disease and Movement Disorders Center at the University of South Florida in Tampa, defines the “Golden Year” for people with Parkinson’s disease to participate in disease modifying clinical trials, offers messages for patients and providers, and tells how a system of referral to entry into clinical trials can work.

Podcast Episode 107: Advocating for a Safe Hospitalization

In this podcast, Rose Lang, an Aware in Care Ambassador for the Parkinson’s Foundation, recounts a challenging hospital visit after her husband, John, fell and broke his hip. She discusses the difficulties of getting medication on time during a hospital stay, and the importance of informing and educating hospital staff about caring for someone with PD.

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