Podcast: Substantial Matters


Every other Tuesday, we bring you a new episode of Substantial Matters: Life and Science of Parkinson’s. Host Dan Keller, PhD, interviews Parkinson’s experts to highlight the treatments and techniques that can help you live a better life now, as well as the research that can bring a better tomorrow. Episodes focus on a range of topics relevant to your daily life, including new levodopa delivery methods, exercise, clinical trials, nutrition and more!

Subscribe: Apple PodcastsGoogle PlayTuneIn (Amazon Echo) or Spotify. You can also subscribe here via RSS Feed. (Need help subscribing? See our guide for help.)

To get started, listen to the episodes in the following playlist, or learn more about each episode below.

Tell us what you think about the podcast here!

Click here to listen to our Spanish episodes

Podcast Episode 99: Nutrition Advice - Part 1

In this podcast, Dr. Duda explains what a whole foods diet is, how it differs from a standard American diet, and how people can reliably and comfortably change the way they eat. More Info

Podcast Episode 98: How to Talk about Impulse Control Disorders

In this podcast, Dr. Gregory Pontone, Director of the Parkinson’s Neuropsychiatry Clinic at Johns Hopkins School of Medicine, a Parkinson’s Foundation Center of Excellence, discusses forms of ICD’s, some means to recognize them, and tools for communicating about them. More Info

Podcast Episode 97: Understanding Bradykinesia and Dyskinesia

In this podcast episode, neurologist Dr. Benjamin Walter describes how bradykinesia and dyskinesia can affect people’s lives, what people can do for themselves to alleviate the discomfort, how they can work with their neurologist to minimize the disorders, and what is in development to help. More Info

Bonus Episode en Español: Acerca del Consejo para personas con Parkinson, o el ‘People with Parkinson’s Council’, de la Parkinson’s Foundation  

In this episode, we hear from Alejandra Borunda, member of the Parkinson's Foundation People with Parkinson's Council. Alejandra shares her experience as a member along with her goals to best reach the Hispanic community throughout her role.

*** In our ongoing efforts to reach all communities whose members may be affected by Parkinson's disease, this week's episode will be in Spanish. We will return with more English language podcasts in two weeks. ***

Podcast Episode 96: PD Medications and Side Effects

In this podcast, neurologist Dr. Irene Richard discusses several of the various drugs and drug classes used to treat the symptoms of PD in relation to the adverse effects that can accompany them. More Info

Podcast Episode 95: The Healing Power of Social Work

In this podcast, Elizabeth Delaney, LCSW, offers suggestions on how people with PD can find a social worker experienced in working with people with progressive diseases. More Info

Podcast Episode 94: Understanding Neurogenic Orthostatic Hypotension

In this podcast, neurologist Dr. Katie Longardner of the University of California San Diego discusses the problem of neurogenic orthostatic hypotension, how it is diagnosed, what people can do to alleviate it, and some of the research she and others are conducting. More Info

Podcast Episode 93: Benefits of Practicing Tai Chi Chuan Exercises

Many people find that Eastern mind-body practices complement Western medicine well and produce additional benefits. One Eastern system of mind-body integration is tai chi and its martial art practice of tai chi chuan. More Info

Veterans Day Bonus Episode

In honor of Veteran’s day, we want to share Lou Eisenbrandt’s My PD Story about her experience as a Vietnam Veteran whose Parkinson’s disease is a result of exposure to the herbicide Agent Orange during the war. More Info

Podcast Episode 92: Clinical Issues Behind Impulse Control Disorders

In this podcast, Dr. Mark Groves, discusses the problem of impulse control disorders, what forms they may take, approaches to recognizing them, and the need to acknowledge them as a biologic condition and not a character or personality flaw. More Info

Bonus Episode en Español: La nutrición y el Parkinson

In this episode, Debbie Polisky, explains to us how to maintain a healthy and active mind through nutrition and how to add certain foods, how anti-inflammatories to improve the diet.

*** In our ongoing efforts to reach all communities whose members may be affected by Parkinson's disease, this week's episode will be in Spanish. We will return with more English language podcasts in two weeks. ***

Podcast Episode 91: The Newly Diagnosed Experience

In this podcast, Anna Hedges relates some of the questions she has fielded from newly diagnosed callers as a Parkinson’s Foundation Helpline Information Specialist for the past ten years. More Info

Podcast Episode 90: Movement Strategies: Mobility, Falls & Freezing of Gait

In this podcast, Heather Cianci says an early consultation can take advantage of a particularly valuable window of opportunity to address movement issues, and improving movement and physical impairments can improve one’s mental state as well.More Info

Podcast Episode 89: Retention Rates in Longer Clinical Studies

Christine Hunter, BSN, RN, describes how her center finds people with Parkinson’s disease who may want to participate in trials, what factors drive retention in trials, and ways to facilitate retention. More Info

Podcast Episode 88: The Skinny on Clinical Trials in PD

In this episode, Dr. Hubert Fernandez, Director of the Center for Neurological Restoration at the Cleveland Clinic in Ohio, a Parkinson’s Foundation Center of Excellence, describes the process of bringing a drug to market, including how many of them never make it. And he explains why people need to participate in the clinical trials and what they can expect when they do. More Info

Podcast Episode 87: What is Lewy Body Dementia and How Does it Relate to Parkinson’s?

In this podcast, Dr. Jennifer Goldman describes the similarities and differences between PDD and DLB, talks about medications and cautions, and offers people with PD important suggestions for coordinating medical care and when accessing care. More Info

Podcast Episode 86: Personalized Medicine: The Voice of the Patient

Dr. Bas Bloem, a professor of movement disorder neurology at Radboud University Medical Center in Nijmegen, the Netherlands, discusses how people with PD want to be heard and how a new definition of health may best put people’s disease into the overall context of their lives. More Info

Podcast Episode 85: Importance of Early Detection of Swallowing Disturbances

SLP Yael Manor, PhD of the Tel Aviv Medical Center in Israel, a Parkinson’s Foundation Center of Excellence, describes the extent of the problem of dysphagia among people with PD, how she evaluates problems, and ways to alleviate them. More Info

Podcast Episode 84: Managing Anxiety with PD

In this episode, clinical psychologist Roseanne Dobkin, PhD, Professor of Psychiatry at Rutgers University in New Jersey, discusses the difference between reasonable worry and problematic anxiety and elucidates some of the ways mental health professionals can help when feelings become distressing or all consuming, interfering with day to day life and activities. More Info

Podcast Episode 83: Staging PD – UPDRS: What it Measures and What Your Score Means

In this episode, Dr. Nina Browner, director of the Parkinson’s Foundation Center of Excellence at the University of North Carolina School of Medicine in Chapel Hill, gives her expert perspective on the use of rating scales and how people with PD may better understand their applicability and how much weight to give the numbers. More Info

Episode 82: Neuropsychological Evaluations for PD

In this episode, Dr. Travis Turner, discusses the role of the neuropsychologist, the process of neuropsychological evaluation, and some of the kinds of problems he deals with. More Info

Episode 81: Practicing Mindfulness Techniques Part 2

In this podcast, Angela Johnson, a doctor of acupuncture and Chinese medicine at Rush University in Chicago, a Parkinson’s Foundation Center of Excellence, gives some simple examples of mindfulness practices, how they may benefit people in periods of stress, and how to fit mindfulness into one’s normal routine. More Info

Episode 80: How Mindfulness Techniques Impact the Nervous System

In this podcast episode, Jordan Staenberg, a doctor of occupational therapy and a certified yoga therapist at the Barrow Neurological Institute’s Muhammad Ali Parkinson Center in Phoenix, Arizona, a Parkinson’s Foundation Center of Excellence, elaborates on what mindfulness means, how one can learn to practice it, and its benefits. More Info

Episode 79: How Clinical Studies Help People with PD

Dr. Tanya Simuni, Chief of Movement Disorders at the Northwestern University Feinberg School of Medicine in Chicago and Dr. Michael Schwarzschild, director of the Molecular Neurobiology Laboratory at Massachusetts General Hospital in Boston, discuss some aspects of clinical studies in PD and why it is important for people with PD to participate in them. Both institutions are Parkinson’s Foundation Centers of Excellence. More Info

Episode 78: Benefits of Self Awareness with PD

Dr. Carsten Eggers, Professor of Neurology and Co-director of the Parkinson’s Foundation Center of Excellence at Philipps University in Marburg, Germany, discusses self-awareness and how health confidence, the confidence to be able to manage health problems, relates to it. More Info

Episode 77: An Aware in Care Success Story

This podcast episode describes a success story of Kathy McMurray and Sara Holman, both of whom were instrumental in educating hospital staff and refining the electronic medical records system to meet the unique needs to treat people with PD. More Info

Episode 76: Practicing Hospital Safety

In this episode, Edie Simpson describes how hospitals typically operate and explains why a person with PD or a care partner must educate hospital staff and be an advocate for the hospitalized person to ensure the best and safest care possible. More Info

Episode 75: Pharmacy Challenges with PD

More Info


Episode 74: A Multidisciplinary Approach to PD

As the director of the Parkinson’s Foundation Center of Excellence at the Royal Derby Hospital in the United Kingdom, Dr. Rob Skelly discusses the makeup of his team and how they approach patients at different stages of Parkinson's and how to provide care with the least burden and disruption on them. More Info

Episode 73: Genetics and PD: What do we know so far?

In this podcast Dr. Martha Nance, medical director of the Struthers Parkinson’s Center in Minneapolis, Minnesota, a Parkinson’s Foundation Center of Excellence, talks about some of the genes related to PD that are under investigation, how they work, and what their effects are, both biologically and in terms of how they may influence the course of the disease. More Info

Podcast Episode 72: What is Deep Brain Stimulation?

In this podcast, Dr. Nader Pouratian, Professor of Neurosurgery and director of the Neurosurgical Movement Disorders Program at the University of California, Los Angeles, discusses how DBS works, what benefits it can and cannot provide, who may be good candidates for it, possible complications, and what’s ahead. More Info

Episode 71: A Western Perspective on PD: Understanding Complementary Medicine

In this episode, Dr. Benzi Kluger, Professor and neuropalliative care specialist at the University of Rochester, a Parkinson’s Foundation Center of Excellence, discusses complementary/alternative medicine from a Western perspective, with an eye on what may be safe to try, as well as some cautions. More Info

Episode 70: The Role of the Microbiome in PD: Part Two

In this episode, Ai Huey Tan of the University of Malaya in Kuala Lumpur, Malaysia discusses what is known about the role of the gut microbiome as it affects Parkinson’s disease and its treatment and what researchers are continuing to investigate. More Info

Episode 69: Parkinson’s Foundation Center of Excellence: What Does it Take and What Does it Mean?

In this episode Clarissa Martinez-Rubio, Senior Director of Clinical Affairs of the Parkinson’s Foundation, describes what these centers are and the criteria for earning a designation as a CoE. Then Joe Salvatore talks about his mother’s experience getting a second opinion at a Parkinson’s Foundation CoE and how it helped change the course of her disease. More Info

Episode 68: The Role of the Microbiome in PD: Part One

Ali Keshavarzian, MD, Chief of the Division of Digestive Diseases and Nutrition at Rush University in Chicago has been studying the role of the gut microbiome and its relation to inflammation, such as in inflammatory bowel disease, in addition to more distant sites including in the brain. His research includes the role of the gut microbiome as a contributing factor to the development and progression of PD as well as the potential to manipulate it to help manage the disease. More Info

Episode 67: PDGENE: Genetic Counseling

The Parkinson’s Foundation has recently initiated the PD GENEration study, which will ultimately recruit and provide genetic testing and counseling to 15,000 people with PD to investigate the relationship between genes and PD. In this podcast, Certified Genetic Counselor Jenny Verbrugge, MS, CGC of Indiana University, a Parkinson’s Foundation Center of Excellence, discusses the role of genetic counseling and the value of home genetic tests versus those performed by a clinical laboratory. More Info

Episode 66: Freezing of Gait

In this episode, Dr. Jay Nutt, Emeritus Director of the Parkinson’s Center at the Oregon Health and Science University in Portland, a Parkinson’s Foundation Center of Excellence, discusses the problem of freezing of gait and offers remedies. More Info

Episode 65: Recognizing Non-motor Symptoms in PD

An awareness of non-motor symptoms and their connection to PD can help people with Parkinson’s find therapists, activities, and solutions that may alleviate the symptoms. In this podcast, Dr. Daniel Van Wamelen of King’s College in London discusses non-motor symptoms and ways to address them. More Info

Episode 64: The Background of the PDGENEration Initiative

In this podcast, neurologist and lead investigator, Dr. Roy Alcalay of Columbia University, a Parkinson’s Foundation Center of Excellence, and patient advocate Anne Hall give some background on the PD GENE genetics initiative. With the aim of uncovering genes and mechanisms responsible for PD, the Parkinson’s Foundation initiated PD GENEration: Mapping the Future of Parkinson’s Disease, a study to look at the genes of 15,000 people with PD and correlate those findings with disease symptoms, progression, and response to treatments. More Info

Episode 63: Navigating Sexuality and Intimacy with PD

In this podcast, Gila Bronner, director of sex therapy services at the Sheba Medical Center in Israel and a Certified sex therapist and researcher at the Movement Disorders Institute at the medical center, talks about some of the sexual problems one may encounter with PD and offers practical advice for dealing with them and enhancing intimacy. More Info

Episode 62: Driving with PD: Limitations, Risks & Adjustments

Dr. Ergun Uč of the University of Iowa has been studying driver safety in PD. He says decisions about fitness to drive should not be based solely on the medical diagnosis or age as these measures alone may unfairly deny people their mobility and independence or may mistakenly allow unfit drivers to stay on the road. More Info

Episode 61: The Launch of the PD GENEration Genetics Initiative

In this podcast, Parkinson’s Foundation Chief Scientific Officer Dr. Jim Beck describes the goals of this Parkinson’s study, how genes affect the course of the disease, and ultimately, how the results of the study may empower people to take better control of their disease. More Info

Episode 60: What is a Disease Modifying Therapy in PD?

In this podcast, Dr. Anthony Lang, Director of the Edmond J. Safra Program in Parkinson’s Disease at the Toronto Western Hospital in Canada, discusses the need for biomarkers when searching for disease-modifying therapies – those treatments that can actually modify the course of PD and not just treat its symptoms. And he tells us why it is sometimes hard to tell the two apart. More Info

Episode 59: Understanding Biomarkers to Deliver Precise Treatments

Neurologist Dr. Alberto Espay of the University of Cincinnati proposes that Parkinson’s research requires a new way of thinking based on biomarkers to know precisely what kind of disease one is dealing with, especially when participating in clinical trials. More Info

Episode 58: Talking to Your Employer About PD Series Part 2: Disability Inclusion and Accommodation at Work

Many people with Parkinson’s disease want to continue to work and contribute their skills in the workplace. Sometimes all it takes is recognition of their condition by their employer and accommodations to compensate for disabilities. In this second of two parts on talking to your employer about PD, Jim Sinocchi, Managing Director of the Global Office of Disability Inclusion at JPMorgan Chase & Company, a multinational investment bank and financial services company based in New York City, describes how the company recruits people with disabilities in their offices worldwide and assimilates them into the work environment. More Info

Episode 57: Talking to Your Employer About PD Series Part 1: Where to Begin?

Employment situations can present a tricky situation for someone with a medical condition such as Parkinson’s disease. Occupational therapist Julia Wood of the Dan Aaron Parkinson’s Rehabilitation Center at the University of Pennsylvania in Philadelphia, discusses when and how to talk with an employer, how to prepare before having the conversation, documenting it, and the decision to also reveal one’s condition to coworkers. More Info

Episode 56: Alleviating Voice Challenges with PD

Just as Parkinson’s disease (PD) affects movements in other parts of the body, it can affect muscles of the face, mouth, and throat, leading to problems with speech and swallowing. Darla Freeman is a Speech-Language Pathologist at the Florida Center for Voice and Swallowing in Tampa with special interests in the evaluation, diagnosis, and management of voice disorders. In this podcast, she discusses voice problems in PD, some methods to alleviate them, and overall communication. More Info

Episode 55: Changing the Hospital Experience through Aware in Care

People with Parkinson’s disease (PD) need their medications on time, every time. So the Parkinson’s Foundation has developed a kit, called Aware in Care, that patients can take with them to the hospital to specify the critical nature of getting medications on time, and the medications that should always be avoided. Annie Wallis, Associate Director of Education at the Foundation, and Leslie Peters, Vice Chair of the People with Parkinson’s Advisory Council for the Foundation, Aware in Care Ambassador, and a care partner for her husband with PD, talk about problems that can arise in the hospital, how to prepare for a hospitalization using the Aware in Care kit, and how the Aware in Care Ambassador program is dedicated to educating hospital staffs around the country to help make the kit most effective. More Info

Episode 54: Understanding Brain Imaging in Parkinson’s Disease

Standard practice in neurology uses imaging, such as magnetic resonance imaging, or MRI, of brain structures to make a diagnosis. But in Parkinson’s disease (PD), additional imaging technologies are needed since MRI is not particularly helpful to make the diagnosis. Recent studies have turned to brain imaging using new technological tools, looking for ways to better assess the disease, predict its progression, and evaluate potential drugs to treat it or slow its progression. Biomarkers that can be seen in this type of brain imaging can be physical structures or biochemical signals, and researchers believe some correlate with the motor abilities of people with PD. Dr. Jon Stoessl of the University of British Columbia in Canada uses positron emission tomography, or PET scans, to research chemical biomarkers in the brain, such as dopamine, for these purposes.More Info

Episode 53: A Look Behind the 2019 World Parkinson Congress

The World Parkinson Coalition (WPC) is a nonprofit organization that provides an international forum on Parkinson's disease and every three years holds the World Parkinson Congress. The 2019 congress will be in Kyoto, Japan in early June, bringing together people with PD, care givers, physicians, scientists, nurses, and rehabilitation therapists for a worldwide dialogue to improve and expedite advances in treatment practices. Through large forums and smaller sessions, attendees will share knowledge and ideas. Eli Pollard, Vice P of Education at the Parkinson’s Foundation and Executive Director of the WPC, says its goal is to bring these diverse constituencies together to engage in high level discussions of a wide range of aspects of Parkinson’s, including treatment, scientific advances, and care options. More Info

Episode 52: Parkinson's Education Through Community Outreach

Workers at the National Neuroscience Institute in Singapore, a Parkinson’s Foundation Center of Excellence, recognized that hospitals and nursing homes cannot handle the impending health care burden themselves and have therefore designed and implemented three community outreach programs to serve people with PD and to educate health care workers how best to serve this population. Dr. Louis Tan of the Department of Neurology describes these programs, how people respond to them, and alliances they have made with other organizations. More Info

Episode 51: Expanding Parkinson's Disease Medical Education

Dr. Sagari Bette of the University of Miami Miller School of Medicine Parkinson’s Disease and Movement Disorders Center, a Parkinson’s Foundation Center of Excellence, says it is important for medical students to get a good foundation in neurology and movement disorders early in order for them to best care for people with Parkinson’s disease and other movement disorders once they are in practice. She explains how medical education is done now and proposes how it could be improved in the future, including the use of educational videos. More Info

Episode 50: Encountering Gender Differences: Women and PD Initiative

Encountering Gender Differences: Women and PD Initiative Edit Section: Basic page pages are not under access control Given the differences women may encounter when dealing with their Parkinson’s Disease (PD), the Parkinson’s Foundation is leading the first national effort to address gender disparities in Parkinson’s research and care as part of an overall Women and PD Initiative. The Women and PD Teams to Advance Learning and Knowledge project (Women and PD TALK, for short) aims to develop new patient-centered recommendations to improve the health of women living with PD. More Info

Episode 49: Parkinson’s Disease vs. Parkinsonism: What’s the Difference?

If a person develops symptoms of tremor, slow movements, and stiffness, it could be early signs of Parkinson’s disease (PD) but it may also be the beginnings of any of a group of conditions known by the general term “parkinsonism,” conditions that have some symptoms in common with PD but differ in important ways. Licensed Clinical Social Worker Paula Wiener, a Senior Parkinson’s Information Specialist with the Parkinson’s Foundation, describes the difference between Parkinson’s disease and parkinsonism. More Info

Episode 48: Seeking a Second Opinion After a Parkinson's Diagnosis

Dr. Carlos Singer, Director of the Division of Parkinson’s Disease and Movement Disorders and the Director of the Parkinson’s Foundation Center of Excellence at the University of Miami Miller School of Medicine in Florida, describes the importance of getting a second opinion from a movement disorders specialist can be a valuable endeavor and about how different people can come to terms with and accept their new diagnosis. More Info

Episode 47: Swallowing Issues and Oral Care with Parkinsons

Everyone should practice good oral health care, but it is particularly critical for people with Parkinson’s disease (PD). Unfortunately, at the time of diagnosis, many people do not receive information about oral health problems that may arise later in the disease.  Dr. Cameron Jeter offers some helpful suggestions to maintain oral care and avoid problems, including dry mouth, drooling, dysphagia, deadly bacteria, and swallowing difficulties. More Info

Episode 46: Addressing Sleep Discomfort with Parkinsons

Most people with Parkinson’s disease have trouble getting a good night’s sleep due to an inability to fall asleep, stay asleep, or get back to sleep if awoken at night. Anne-Louise LaFontaine, Director of the McGill University Movement Disorders Clinic in Montreal, Canada, a Parkinson’s Foundation Center of Excellence, discusses the problems and offers solutions. More Info

Episode 45: Patient Engagement in Research: The Parkinson’s Advocates in Research Program (PAIR)

In this podcast, Karlin Schroeder, Director of Community Engagement at the Parkinson’s Foundation, and Kevin Kwok, a Research Advocate in the PAIR program, describe the program, its aims, and how to get involved for anyone wishing to become an advocate. More Info

Episode 44: Talking to Children About Parkinson's

In this second episode of our two-part Holiday Series: Families and Parkinson’s, Soania Mathur, MD, CCFP, offers advice about how to talk to children about Parkinson's, where to turn for resources, and even how having a parent, grandparent, or other relative with a chronic disease can have positive aspects for a child. More Info

Episode 43: Parenting and Parkinson's: Raising Children While Living with Parkinson's

Social worker Elaine Book of the Pacific Parkinson’s Research Center and the University of British Columbia Movement Disorders Clinic shares how she helps families cope with Parkinson's disease by discussing some of the new challenges and demands, what changes may occur in the family, and those things that remain the same. More Info

Episode 42: Music Therapy for Parkinson's

Music therapist Dr. Concetta Tomaino, Executive Director and co-founder of the Institute for Music and Neurologic Function in Mount Vernon, New York, discusses who can benefit from music therapy, how it is done, what neuroscience research has found, and where to find information on music therapy, including the multiple ways therapy can alleviate some problems associated with Parkinson’s. More Info

Episode 41: Palliative Care as Supportive Care in PD

Benzi Kluger, MD, MS, director of the University of Colorado’s Neurology and Supportive Care clinics, says that palliative care should begin at the time of diagnosis. He describes the results of a new Parkinson’s study and how it benefited participants who received it and viewed it as ‘supportive care’, as well as how palliative care can be incorporated into daily routines for people with Parkinson’s. More Info


Episode 40: Dance Therapy for PD

Erica Hornthal, LCPC, BC-DMT describes DMT, how DMT therapists are trained, what goes on during a therapy session, and how people can find a therapist or program. More Info

Episode 39: PD Across Race & Ethnicity: Outreach to the African American Community

Dr. Reversa Joseph, a movement disorders specialist and Adjunct Assistant Professor of Neurology at the Ohio State Wexner Medical Center, discusses outreach, education, and perception in the African American community and her efforts to raise awareness of Parkinson's. More Info

Episode 38: More Than a Movement Disorder: Addressing Mood and Coping

Licensed Clinical Social Worker Jessica Shurer discusses the emotional changes that may occur throughout the course of Parkinson's disease along with suggestions for how people who are unable to travel to large medical centers may find help to address their emotional needs. More Info

Episode 37: Mental Health in a Medical Setting

Mental health issues are often a part of a chronic disease such as Parkinson’s, but no one comes into a disease as a blank slate. Licensed Clinical Social Worker Kara Barton discusses how to recognize mental distress, ways to access care, the healthcare providers who can help, and possible ways of getting care when insurance does not cover it. More Info

Episode 36: Depression in Parkinson's

 Dr. Richard discusses how people with PD and their families should have an increased level of awareness of what depression may look like and feel confident about bringing it up with their healthcare team. More Info

Episode 35: Preclinical Models of PD

 Richard Smeyne is a professor of neuroscience and director of the Jefferson Comprehensive Movement Disorder and Parkinson’s Center at Thomas Jefferson University in Philadelphia, and discusses the value of research on preclinical models of PD. More Info

Episode 34: New Pathways & Drug Development

Doctor Michael Okun discusses Parkinson’s disease mechanisms as possible targets for drug development, current drug statuses, and how to increase the process of bringing a drug to market to help people with Parkinson's. More Info

Episode 33: The Parkinson’s Prevalence Project

James Beck believes the number of people living with Parkinson’s in the United States has been dramatically underestimated and does not represent the ethnic diversity of people affected. He explains Parkinson’s Prevalence Project is designed to give a clearer picture of PD in North America. More Info

Episode 32: The Development of the Parkinson's Outcomes Project

Fernando Cubillos, Director of Research Programs for the Parkinson’s Foundation, discusses leading the largest clinical study of Parkinson's to date. More Info

Episode 31: Allied Team Training for Parkinson’s

Ruth Hagestuen, founder of ATTP, discusses the the history and future of ATTP as she transitions out of her role. More Info

Episode 30: Team Care for PD: Why It’s Important

Lisa Mann discusses team care for people with Parkinson's and how rehab therapists and health care professionals can be brought in to help as needed. More Info

Episode 29: Home Care Program for Advanced PD

Dr. Jori Fleisher of the Rush University Medical Center Movement Disorders Program in Chicago, a Parkinson’s Foundation Center of Excellence, helped develop a home visit program to address this issue when she was at New York University Medical Center. More Info

Episode 28: Autonomic Problems

Dr. Tanya Gurevich focuses on symptoms and challenges beyond movement problems, how a comprehensive, team approach can benefit people with Parkinson's with matters such as blood pressure drops, urinary symptoms, sleep disturbances, sexual and intimacy matters, and other quality of life issues affecting them and their caregivers. More Info

Episode 27: More Than Movement: Addressing Cognitive and Behavioral Challenges in Caring for PD

Dr. Jennifer Goldman discusses some of the cognitive and behavioral care challenges and offers advice for ways to address them. More Info

Episode 26: Medical Marijuana - Going Green for Parkinson's?

Dr. Danny Bega of Northwestern University’s Parkinson’s Disease and Movement Disorders Center in Chicago, a Parkinson’s Foundation Center of Excellence, sheds light on some of the issues and concerns surrounding the use of medicinal cannabis for people with Parkinson's. More Info

Episode 25: Meet the High School Student Who Is Changing Parkinson's Disease Diagnosis

Erin Smith of Shawnee Mission West High School adapted a real-time facial expression recognition system to detect “facial masking,” a common Parkinson’s symptom caused by stiff facial muscles. Her system, called FacePrint, analyzes facial movements and compares them to a database of people with and without Parkinson’s. More Info

Episode 24: Donate Your Brain for Parkinson's Research

Tish Hevel, founder and CEO of the Brain Donation Project, explains how to become a brain donor, as well as dispelling some misperceptions about the subject. More Info

Episode 23: Hallucinations and Delusions in Parkinson’s 

Dr. Martha Nance explains the causes of sensory misperceptions (hallucinations or illusions) or false beliefs (delusions), gives examples of how people with Parkinson’s might experience them and discusses coping mechanisms and considerations for medical management. More Info

Episode 22: Do You See What I See? Hallucinations and Parkinson’s Disease 

Dr. Joseph Quinn, professor of neurology at the Oregon Health and Science University in Portland, a Parkinson’s Foundation Center of Excellence, discusses hallucinations and how people with PD can deal with it. More Info

Episode 21: What Other Conditions Are Related to Parkinson’s?

Dr. Connie Marras discusses Parkinson’s comorbidities (conditions you have in addition to PD), how to avoid some of them and what to know about drug interactions. More Info

Episode 20: Medical-Community Partnership for Parkinson’s Wellness

Clinical social worker Amy Lemen describes the Wellness Initiative program, what it offers, who can participate and how. More Info

Episode 19: Ask the Parkinson’s Foundation Helpline: Your Exercise Questions Answered

Jill McClure, an information specialist on with the Parkinson's Foundation Helpline, discusses exercise as medicine and her professional insights. More Info

Episode 18: Stall the Fall

Dr. Sotirios A. Parashos discusses the critical, supporting role that a medical team has in helpling live a better life. More Info

Episode 17: Stem Cells and Parkinson’s

Dr. Okun discusses the alpha-synuclein protein and links to the development of Parkinson's. More Info

Episode 16: Can an Asthma Drug Prevent Parkinson’s?

Dr. David K. Simon describes what the researchers did and what they found. More Info

Episode 15: Why and How to Participate in Parkinson’s Research

Christine Hunter describes the value of volunteering for clinical trials and how participants view their experiences. More Info

Episode 14: Clinical Trials for Parkinson’s

Tanya Simuni, MD, explains the clinical trials process and describes some ongoing trials, including how the potential new drugs work and why it’s important for people with Parkinson’s to participate in research. More Info

Episode 13: Generic Drugs for Parkinson’s

Dr. Rajesh Pahwa of the University of Kansas describes how generics compare to brand name products and what to look for and look out for. More Info

Episode 12: What We’ve Learned from the Hispanic Parkinson’s Community

Claudia Martinez discusses differences in the access to information across communities and her practices on providing the best possible care to the Hispanic community. More Info

Episode 11: Extending the Reach of Parkinson’s Resources and Services

Aaron Daley of the University of California, San Francisco, describes his center’s outreach efforts and what is needed to bring Parkinson’s resources to underserved and underrepresented communities. More Info

Episode 10: Young-Onset Parkinson’s 101

Elaine Book, MSW, RSW, discusses the particular challenges of YOPD like disclosure, planning for the future, and controlling the disease. More Info

Episode 9: Keys to Driving with Parkinson's

Lissa Kapust, LICSW, discusses the complications of driving while having Parkinson's and a program aimed at assessment in a variety of areas. More Info

Episode 8: A Vaccine for Parkinson's?

Mark Guttman, MD discusses the potential of using vaccines to clear abnormal forms of alpha-synuclein from the brain. More Info

Episode 7: Genetics as a Guide to Neuroprotection in Parkinson's Disease

David K. Simon, MD, PhD, explains how modern genetics can be a guide to developing new drugs for Parkinson's. More Info

Episode 6: New Levodopa Delivery Methods for Parkinson’s

More than 50 years after its discovery, levodopa is still the most effective treatment for Parkinson’s, but some people experience “off” periods or dyskinesias with oral medications. Dr. Mark Guttman describes new delivery methods that promise to help with some of these problems, especially for people who have had Parkinson’s for many years. More Info

Episode 5: How to Manage Parkinson’s “Off” Time

Parkinson’s can be unpredictable – symptoms can come and go or get better and worse throughout the day. These so-called “on-off” fluctuations (also called motor fluctuations) and dyskinesias can be troubling, but movement disorder specialists can help with the choice of medication, dosages, and timing. Dr. Irene Malaty explains more about what causes these changes and how you can work with your doctor to manage them. More Info

Episode 4: The Importance of Good Nutrition for People with Parkinson’s

Nutrition is increasingly part of the conversation when it comes to good Parkinson's care. Dr. Bas Bloem describes how diet can help improve some of the symptoms of Parkinson's and optimize the effects of medication, and he offers tips on getting adequate nutrition. More Info

Episode 3: The Benefits of Exercise for People with Parkinson's

Regular exercise is essential for people with Parkinson's. Dr. Bas Bloem describes what is known about exercise and PD and what is still in the research stages, and he offers some tips on overcoming barriers to getting enough exercise. More Info

Episode 2: The Parkinson's Foundation’s Role in Improving Standards of Care

Dr. Peter Schmidt of the Parkinson’s Foundation explains where people with Parkinson’s can go to receive the best interdisciplinary care and how the Foundation is improving standards of Parkinson’s care around the world. The Foundation's Centers of Excellence network and the Parkinson's Outcomes Project are key aspects of the discussion. More Info

Episode 1: Early Warning Signs of Parkinson's

In this debut episode of Substantial Matters: Life and Science of Parkinson's, Dr. Michael Okun talks about early warning signs of Parkinson's and offers practical advice on how to proceed after a diagnosis. More Info

mail icon

Subscribe here to get the latest news on treatments, research and other updates.