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Research

What's Hot in PD? Accumulating Evidence for a Role of Gut Microbiota in Parkinson’s Disease

Date: 
Tuesday, December 6, 2016
Author: 
Dr. Michael S. Okun

Considerable evidence has been mounting in support of a relationship between the gastrointestinal (GI) system and Parkinson’s disease (PD). Many pathologists and neurologists even believe that Parkinson’s may start in the gut, but this view remains speculative. Many GI symptoms, such as constipation, occur as prominent and disabling PD symptoms. In the July 2013 What’s Hot in PD? column, I addressed H.

Research Round Up: NPF Study Sheds New Light on Parkinson’s and Dyskinesia, Antipsychotic Medication, Injury and Fall Rates

Date: 
Thursday, November 17, 2016
Author: 
National Parkinson Foundation

Who has the highest risk of injury among people with Parkinson’s disease (PD)? Is there a connection between medication combinations and falling less? Are prescription antipsychotics safe? Earlier this year, NPF presented four posters at the World Parkinson Congress (WPC) that answered these questions and more.   

What's Hot in PD? Lymphoctye Activation Gene 3 (LAG3) Antibodies as a Potential Future Treatment for Parkinson’s Disease

Date: 
Tuesday, October 4, 2016
Author: 
Dr. Michael S. Okun

Ted Dawson, PhD, and colleagues at the Johns Hopkins University, a National Parkinson Foundation Center of Excellence, have uncovered a potential new approach to treat Parkinson’s disease (PD). Researchers in Dawson’s laboratory focused on a protein called lymphocyte-activation gene 3, known as LAG3. This protein has been shown to be important in cell to cell transfers of α-synuclein (Lewy bodies), which is a protein found in the brain of a person with PD.

Research Round Up: New Hope for Better Treating Psychosis

Date: 
Monday, October 3, 2016
Author: 
Fernando Cubillos, MD, NPF Director of Research Programs

While reviewing data from the National Parkinson Foundation’s (NPF) Parkinson’s Outcomes Project a year ago, I noticed a participant whose quality of life went from pretty good to terrible, then back to pretty good. I wondered, “what happened here?” The answer: psychosis.

What's Hot in PD? The Importance of Imaging Biomarkers to Diagnose and Track Parkinson’s Disease Progression

Date: 
Wednesday, August 31, 2016
Author: 
Dr. Michael S. Okun

A recent press release from the National Institutes of Neurological Disorders and Stroke detailed exciting ongoing work aimed to uncover magnetic resonance imaging (MRI) techniques capable of tracking Parkinson’s disease (PD) progression. In this month’s What’s Hot in PD? column we will review the recent progress of MRI-based biomarkers for Parkinson’s diagnosis and progression, and discuss the importance of the findings, especially in the context of clinical trials.

Research Roundup: A Word of Caution on the Recent Findings about Physical and Occupational Therapy Effectiveness

Date: 
Thursday, February 11, 2016
Author: 
Miriam Rafferty, PT, DPT, PhD, NCS

Several troubling headlines appeared recently after a large randomized controlled study, published in the American Medical Association’s neurology journal (JAMA Neurology), concluded that physical therapy (PT) and occupational therapy (OT) did not improve activities of daily living in people with Parkinson’s disease (PD).

Research Roundup: Sex and Parkinson's Disease

Date: 
Tuesday, December 29, 2015
Author: 
Dr. Nabila Dahodwala

This is the first part of a series of videos discussing sex differences in Parkinson's disease. The video was created from a presentation given by Dr. Nabila Dahodwala from the University of Pennsylvania. The National Parkinson Foundation recently announced that it awarded Dr. Dahodwala a two-year grant to study issues that result in differences in caregiving and to explore whether there may be options to improve caregiving. Dr.

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