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Science News

Parkinson’s Foundation researchers and other scientists worldwide make continual advances in understanding Parkinson’s disease (PD) with revolutionary research. We monitor it all in our effort to improving care and advance research toward a cure. Browse our collection here:

Liver Drug Studied as Potential Parkinson’s Treatment
Friday, September 11, 2015

A drug used for treating liver disease shows potential as a therapy for slowing the progression of a genetic form of Parkinson’s disease (PD), according to research published in the August 7 online edition of Neurology. In experiments with cells and fruit flies, the drug reversed cellular damage caused by a mutation in the geneknown as LRRK2.

Brain “Talk” Helps Researchers Discover Circuit Underlying Dyskinesia in Parkinson’s
Thursday, September 3, 2015

In the September 2 edition of Neuron, researchers report the discovery of changes in the brain that happen in Parkinson's disease (PD) further downstream of where dopamine sends its message. They noted supersensitivity in these neurons that could also explain dyskinesia – the involuntary movements that often come with dopamine therapies.

Two Studies Examine Diabetes Drugs in PD
Tuesday, August 25, 2015

Two clinical studies investigating a class of type 2 diabetes drugs for Parkinson’s disease (PD) are helping scientists to better understand PD and if there are possible uses for these drugs. The studies respectively found that extended treatment with one specific drug does not improve PD symptoms, but that people who take one in the class of drugs may have a lower risk of PD.

Taiwanese Study Suggests PD Increases Risk for Most Cancers
Monday, August 17, 2015

A new study of a large sample of people living in Taiwan reports that having Parkinson’s disease (PD) increases one’s risk for later developing most types of cancer, underscoring the importance of ethnicity and environmental exposure when computing risks. The results were published online June 18 in JAMA Oncology.

New Deep Brain Stimulation Device Holds Promise for Better Therapy
Wednesday, August 12, 2015

A new technique for delivering deep brain stimulation (DBS) may provide a way to individualize this therapy, and lessen side effects, for some people with Parkinson’s disease (PD). A study published in the July edition of Lancet Neurology found that the technique, which can deliver more focused electrical stimulation at higher levels, safely improved PD symptoms.

Traumatic Brain Injury Late in Life Increases Parkinson’s Risk
Friday, June 5, 2015

People aged 55 and older who were treated in the hospital for traumatic brain injury were 44 percent more likely to develop Parkinson’s disease (PD) over the next six years than those who sustained injuries, but not head injuries, according to research published in the March 28 online edition of Annals of Neurology.

New Guidelines for Treating Orthostatic Hypotension in PD
Tuesday, June 2, 2015

A new study suggests updated diagnosis and treatment guidelines for people with Parkinson’s disease (PD) who experience orthostatic hypotension (OH), a rapid drop in blood pressure which often occurs when changing positions into an upright position (e.g., getting out of bed or standing up after sitting). The findings were published online February 12 in Movement Disorders.

Scientists Flip a “Light Switch” to See How Transplanted Dopamine Neurons Work
Wednesday, May 27, 2015

With a technique that uses light to turn cell activity off and on, scientists have shown that neurons transplanted into mice with Parkinsonian symptoms can integrate into the brain and release dopamine. The study appears in the January 12 online edition of Nature Biotechnology, and was supported in part by the Parkinson’s Disease Foundation (PDF).

Scientists Identify a New Parkinson’s Disease Gene
Wednesday, May 20, 2015

By studying the genes of a large family in which eight members across two generations were affected by Parkinson’s disease (PD), researchers have identified a new genetic mutation that may cause PD. The results appear in the March edition of The Lancet Neurology.

Parkinson’s Affects Both Low- and High-Contrast Vision
Wednesday, May 20, 2015

A new study confirms that people with Parkinson’s disease (PD), as compared to healthy individuals, experience trouble with certain aspects of vision, including contrast sensitivity (e.g., distinguishing between shades of gray) and using high-contrast vision at a distance. The results appear in the February 17 online edition of the Journal of Parkinson’s Disease.


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