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Science News

Parkinson’s Foundation researchers and other scientists worldwide make continual advances in understanding Parkinson’s disease (PD) with revolutionary research. We monitor it all in our effort to improving care and advance research toward a cure. Browse our collection here:

Chemical Markers of Inflammation Linked to Parkinson’s
Thursday, October 13, 2016

Blood levels of cytokines — substances associated with inflammation — are higher in people with Parkinson’s disease (PD) than in healthy individuals, according to research published in the September 26 online edition of JAMA Neurology. The results add to mounting evidence linking PD and inflammation, and point to potential biomarkers for diagnosing and monitoring PD.

Single Cause May Underlie Both Genetic and Sporadic Parkinson’s
Tuesday, October 11, 2016

Research published in the September 8 edition of Cell Stem Cell finds that a common molecular mechanism may underlie all cases of Parkinson’s disease — both the majority in which the cause is unknown and the rare cases which result from genetic mutations. The discovery paves the way for developing a biomarkerfor early detection and new therapeutic approaches.

FDA Approves St. Jude Medical Infinity DBS System for People with PD
Thursday, October 6, 2016

The Parkinson’s Disease Foundation (PDF) alerts the community that St. Jude Medical Infinity Deep Brain Stimulation (DBS) system has been approved by the US Food and Drug Administration (FDA) for the treatment of people living with Parkinson's. The manufacturer reports that its new system is designed to provide targeted control of Parkinson’s symptoms with fewer side effects.

Parkinson's Disease Foundation Addresses Unmet Needs in Parkinson's Education with Newest Online Seminars
Tuesday, September 13, 2016

Free Seminars Provide Practical Tips for People Living with Parkinson's and Continuing Education for Health Professionals

Formula of Probiotics and Fiber Reduces Constipation in Parkinson’s
Wednesday, August 24, 2016

A daily dose of an experimental fermented milk drink, which contained probiotics (bacteria that aid digestion) and fiber, helped to reduce constipation in people with Parkinson’s disease (PD) according to a new study. The results appear in the August 19 online edition of Neurology.

New Formulation of Old Drug Shows Promise for “Off” Episodes
Monday, August 22, 2016

Administering an approved drug, apomorphine, by a new method — dissolving it under the tongue — can relieve “wearing off” episodes for people with Parkinson’s disease (PD), according to the results of a small, phase II clinical trial. The study appears in the July 19 online edition of Movement Disorders.

Key Enzyme Regulates Brain Cell Change in Parkinson’s
Monday, August 1, 2016

In studies with laboratory mice, scientists have identified a single molecule, an enzyme called c-Abl, that regulates the build-up of toxic alpha-synuclein protein in brain cells. Such protein clumps, known as Lewy bodies, are the hallmark of Parkinson’s disease (PD). The finding suggests that blocking the enzyme may be an effective approach for new therapies to treat PD.

Parkinson’s Biomarker Detected in Urine
Thursday, July 28, 2016

Researchers have discovered a substance in urine that may serve as a biomarkerfor predicting Parkinson’s disease (PD) risk and monitoring the progress of the disease. The results appear in the March 15 issue of Neurology and the June 15 online edition of Movement Disorders. The work was supported in part by the Parkinson’s Disease Foundation.

Molecule that Targets Alpha-Synuclein Points Toward Potential Parkinson’s Therapy
Thursday, July 28, 2016

In laboratory studies with cells, scientists have identified a new molecule that may be able to help clear toxic protein clumps from the brain in Parkinson’s disease (PD). Its discovery begins a long road of research that potentially lead to a new therapy for PD. The study appears in the July 13 edition of The Journal of Neuroscience.

Teasing Apart Two Sets of Dopamine Neurons to Understand Parkinson’s
Monday, July 18, 2016

Researchers may have solved a long-standing puzzle about the brain cells that are lost in Parkinson’s disease (PD). The study, published in the July 11 online edition of Nature, finds that there are two distinct types of dopamine neurons lost in PD. Not only that, the study finds that each kind of neurons controls different types of behaviors, which could help scientist better target PD treatments.


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