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Parkinson's Outcomes Project

Our most exciting study underway

The National Parkinson Foundation has invested millions of dollars in research to help improve the lives of people with Parkinson’s. Our most exciting study is underway now: the Parkinson’s Outcomes Project.

Started in 2009, the Parkinson’s Outcomes Project is the largest-ever clinical study of Parkinson’s disease with nearly 10,000 patients in four countries. This ground-breaking initiative enables us to track and monitor the care over time of patients who are seen at NPF Centers of Excellence.

What makes this project truly innovative is that it studies everyone with Parkinson’s, from the newly-diagnosed to people who have lived with Parkinson’s for 20 years or more, providing us with a comprehensive view of the disease and its overall impact on people’s lives.

Our unique study evaluates a wide-range of factors of Parkinson’s including:

  • Most effective Parkinson’s treatments
  • Benefits from therapy
  • Best candidates for each treatment
  • Benefits of various exercise programs
  • Impact on caregivers

Research has shown that the better we manage Parkinson’s today, the better life will be tomorrow. In addition to finding better treatments for people with Parkinson’s, and sharing models of excellent care with health professionals, we’re working to ensure that every patient receives the best possible care, no matter where they’re seen.  

The Parkinson’s Outcomes Project research highlights:

  • Interventions that provide neuroprotective benefits, such as exercise, could change the course of the disease.
  • Patients receive different medicines and treatment plans depending on where they receive care, with vastly different results.
  • Increasing physical activity to at least 2.5 hours a week slows the decline in quality of life.
  • Regular neurologist care could save the lives of thousands of people each year.
  • Depression and anxiety are the number one factors impacting the overall health status of patients.

The National Parkinson Foundation is focused on what people with Parkinson’s need today. Your investment and support allow us to help people live their best lives now until there is a tomorrow without Parkinson’s.

View the list of principal investigators and advisors.

Read about NPF’s latest findings:

A National Parkinson Foundation Study Finds that Regular Exercise Can Slow Decline in Quality of Life
Meet the NPF Researcher: Dr. Anhar Hassan
NPF Announces New Findings from Largest-Ever Parkinson’s Study of 8,000 Patients Worldwide

To find out if we are enrolling patients in the study at a center near you, visit