This week the FDA approved the drug Pimavanserin (Nuplazid) for the treatment of Parkinson’s disease psychosis. There has been a critical, unmet need for development of better drugs to address hallucinations and psychosis in the setting of Parkinson's disease. We have learned over many years that typical high potency neuroleptic antipsychotic drugs (e.g.
Blog Introduction Text
Welcome to the National Parkinson Foundation's blog, where you can keep up-to-date on the latest research, read about what's hot in the Parkinson's community, learn caregiving tips and more.
Beth Coffman lives in Traverse City, Mich., and is 79 years young. She is a wife, mother, grandmother, great grandmother and a member of numerous community groups. Five years ago Beth learned that she has Parkinson’s disease (PD). After retiring from her 40-year teaching career she still strongly believes in the power of information, which is why she calls the National Parkinson Foundation (NPF) Helpline.
Yoga can benefit both persons with PD and their care partners, but often people don’t know how to get started. This is part one; tune in next month for part two!
The last two decades have observed a strong push to initiate dopamine agonist therapy for many Parkinson’s disease patients. However, recently there has been a move away from this approach. The hesitation about agonist therapy has mainly concerned the worrisome impulse control-related side effects, though there are other potential adverse effects reported from agonist use.
Several troubling headlines appeared recently after a large randomized controlled study, published in the American Medical Association’s neurology journal (JAMA Neurology), concluded that physical therapy (PT) and occupational therapy (OT) did not improve activities of daily living in people with Parkinson’s disease (PD).
There has long been speculation that viral infection may cause dopamine responsive Parkinson’s disease — at least in a subset of patients. The most famous case examples were depicted in the 1990 movie Awakenings starring Robin Williams and Robert De Niro (based on Oliver Sacks’ 1973 memoir) where Parkinsonian patients (presumed to have been suffering from a viral flu or sleeping sickness) awaken when exposed to dopamine.
Many families and caregivers seek the answer to the question, “What should I do with Dad? He just wants to sit and watch TV all day.”
Together, you and NPF made 2015 a year of spectacular progress for everyone with Parkinson’s and their families. We are pleased to share these highlights with you:
Tea is an ancient, centuries-old beverage that is consumed by virtually all of the world’s population. Tea is composed of polyphenols, methylxanthine, caffeine, fats, amino acids and other substances. Tea has been thought to reduce cancer risk, prevent heart disease and even aid in weight loss. The flavonoids, caffeine and theanine have been tested in animal models of Parkinson’s disease and have shown protection against cell loss in similar areas of the brain that are affected in the human Parkinson’s patient.